During these uncertain times, how can we help?

As the world leader in volunteerism we feel a responsibility to unite our broader community, and to use this moment to become stronger.

See below to access our COVID-19 Resource Hub, and to explore our growing directory of COVID-19-specific and virtual volunteering opportunities.
Read More

P.R.I.S.M.S., Inc.

Cause Area

  • Children & Youth
  • Community
  • Health & Medicine
  • People with Disabilities


21800 TOWN CENTER PL STE 266A-633STERLING, VA 20164 United States

Organization Information

Mission Statement

PRISMS, an acronym for Parents and Researchers Interested In Smith-Magenis Syndrome, is dedicated to providing information and support to families of persons with Smith-Magenis Syndrome (SMS), sponsoring research and fostering partnerships with professionals to increase awareness and understanding of SMS.

Smith-Magenis syndrome (or SMS) is a chromosomal disorder characterized by a recognizable pattern of physical, behavioral, and developmental features. It is caused by a missing piece of genetic material from chromosome 17, referred to as deletion 17p11.2.

Common features include: characteristic, yet subtle, facial appearance, infant feeding problems, low muscle tone, developmental delay, variable levels of intellectual disability, early speech/language delay, middle ear problems, skeletal anomalies and decreased sensitivity to pain. The syndrome also includes a distinct pattern of neurobehavioral features characterized by chronic sleep disturbances, arm hugging/hand squeezing, hyperactivity and attention problems, prolonged tantrums, sudden mood changes and/or explosive outbursts and self-injurious behaviors.


PRISMS serves as a central clearinghouse for information about SMS, providing a range of educational and support services, including:


Would you recommend P.R.I.S.M.S., Inc.?
0 reviews Write a review

Report this organization